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RSO Oil: All You Need to Know for Pain Relief

RSO is a type of cannabis concentrate that has become popular in the last few years because of its potential therapeutic benefits. This guide will highlight everything you need to know about RSO, including its history, how it’s made, and dosing information. You’ll also learn how it’s used to manage pain and other conditions.

What Is RSO Oil?

RSO, also called Rick Simpson Oil, is a highly potent cannabis oil with a dark color and thick consistency. The oil contains high levels of tetrahydrocannabinol (THC), unlike other types of cannabis oils on the market.

RSO was originally made by a Canadian scientist called Rick Simpson, hence the name. He created the oil in 2003 after he was diagnosed with basal cell carcinoma. Because he had experienced some success treating other illnesses before, he decided to try treating his condition using THC cannabis oil. Apparently, he read a particular study by the Journal of the National Cancer Institute where THC had been used to reduce cancerous cells in mice.

This led to him making a cannabis oil which he applied to the cancerous spots on his skin. After a few days, allegedly, the spots had disappeared. When he consulted with his doctor about it, the doctor refused to acknowledge those benefits. Still, Simpson started creating the oil anyway and proclaiming the benefits.

How RSO Oil Is Made and Its Composition

Many people have used this oil for various conditions because it’s easy to prepare. Here’s how to make RSO.

  • Mix cannabis with alcohol (Grain alcohol is the commonly used solvent). As you mix, crush and stir the cannabis to allow THC to dissolve and lead to a higher concentration.
  • Strain the solvent using a cheesecloth to eliminate the remaining plant materials
  • Heat the solvent (avoid naked flames) to eliminate the alcohol and contaminants present.

You’ll be left with a thick, dark-colored oil. Although RSO contains high levels of THC, you can find oils with varying rations. For instance, you can get one with 90% THC while another will contain 60% CBD and 40% THC. There are also balanced oils with a 1:1 ratio of THC and CBD.

How to Use RSO Oil

Before asking how to use RSO, you’ll want to talk to your physician first. With the right medical guidance, this oil has been found to be an alternative form of treatment for various conditions. In addition, understand that RSO shouldn’t replace the standard treatment unless your doctor suggests it.

So, what is RSO oil used for, and how is it taken? RSO is used to manage several health conditions. The common way to use this oil is through cannabis syringes, where you can dispense the exact amount of oil you want for your food or drink. It’s advisable to consume RSO while full because of its high potency. Other ways to consume RSO include the following.


You can consume RSO through capsules. An RSO capsule still has the same benefits as syringes, only that it comes in easy-to-swallow pills. This mode of consumption isn’t recommended to newbies. It’s better to start with the syringe because you can control the amount you consume. But once you understand the RSO dosage that works for you, you can move to capsules, as they are the most convenient dosing option.


The other way is through tinctures. Often combined with MCT oil, an RSO tincture is a great way to ease into your RSO regimen. The amount of THC in tincture drops is less than that found in a syringe drop.


Other people also take RSO in the form of edibles. And while you can add this oil to foods, don’t expose it to temperatures over 300ºF because it can burn the cannabinoid. It’s best to add it to already-cooked food like soups and salads.

Topical Application

When Simpson created RSO, he used it as a topical. And while there are now other ways to use it, RSO topical for pain is still popular. You can rub it on the skin near the area you want to treat. Since the RSO doesn’t enter your bloodstream, you won’t experience psychoactive effects. Reapply every day to experience the benefits.

If you’re thinking of smoking RSO instead of using it topically or ingesting it, ensure the oil used is right. If you plan to prepare it yourself, burn the alcohol completely before smoking it. This method of ingestion is often not recommended because if the RSO has some alcohol remaining, it can be combustible and harm you.

How to Determine the Right Dosage and Dosing Information

How much RSO should I take? Most people ask this question when they start using this oil. The truth is that each person has their ideal dose. However, considering that it contains high levels of THC, it’s wise to begin with low doses, specifically 60 grams in 90 days.  

During the first week, start with three doses daily, each after every 8 hours. The first dose should be as small as half a grain of rice or a quarter of a drop. After four days, you can double the dose. You’ll still take it three times a day, with your first dose in the morning. It takes about 3 to 5 weeks to start taking one gram or one ml daily.

What Are the Side Effects of RSO?

As mentioned,  RSO contains a higher concentration of THC. Therefore, you’re likely to feel intoxicating effects like paranoia, sleepiness, dizziness, irritability, and red eyes. These RSO effects will reduce as your tolerance starts growing. This often happens after 3 to 4 weeks. Also, proper RSO dosing, especially when starting off, can help reduce some of these side effects.

Does RSO get you high? RSO will get you high because it contains higher levels of THC, the main psychoactive component in marijuana. Simpson argued that RSO aided in his cancer delivery. As such, a lot of formulators still use his ingredient baseline, which includes a high THC content.

These side effects of RSO are temporary. However, because of the high THC levels, consuming too much of it can lead to serious effects like paranoia and tachycardia. Also, this is a drug that will impair your judgment. As such, don’t operate heavy machinery or drive after consuming RSO, as it can lead to accidents.

If you’re under any medication, it’s best to consult your doctor before taking this cannabis oil. The physician will inform you whether there are potential negative effects if your medication interacts with RSO. Some of the medications that can negatively interact with RSO include opioids, antidepressants, and sedatives.

RSO for Pain Relief

Cannabis has been found to be effective in pain management. And because RSO is a form of cannabis, it can help relieve pain. In fact, RSO for pain is the major reason people consume this product.

So, how does this work? Your body has a system called the endocannabinoid system. It’s responsible for many body functions, including appetite, sleep, and pain sensation. The THC in RSO binds with cannabinoid receptors in your endocannabinoid system, mostly concentrated in the nerve and brain cells. When the THC binds to nerve receptors, it lessens the pain sensations.

Success Stories of RSO for Pain Relief

There have been a few success stories of using RSO for pain relief. Newton Jon, a cancer patient, says that this oil has helped manage pain to the point where she no longer uses morphine. She reports that she knows it’s working because she feels pain when she doesn’t take the drops. The cannabis oil has also helped her with sleep and anxiety.

Another success story is from a Fibromyalgia patient who was experiencing chronic pain because of multiple injuries. Despite taking different medications, including oxycodone and naproxen, the 53-year-old was still in significant pain. The doctor suggested medical marijuana, and after a few months, he was off his prescribed pain medication.

RSO Oil for Other Health Benefits

Aside from pain relief, RSO has other health benefits. Because Rick Simpson invented it to cure his skin cancer condition, most people wonder if using RSO for cancer is a good idea. Evidence shows that cannabis oils with THC can help reduce the side effects of cancer treatments, such as vomiting and nausea. It can also reduce pain and enhance appetite. Aside from that, it can also be used in epilepsy patients to reduce seizure activity,

Official research concerning this oil’s ability to cure cancer is limited. Because the government categorizes marijuana as a Schedule I drug, not many scientists have given it much attention. However, those who have, have found that it can help with cancer treatment when combined with other types of therapies. Still, no conclusive report shows that RSO oil treats cancer.

The Potential Risks Associated With Using RSO as a Form of Treatment

While RSO has helped many patients with different health conditions, you should lower your expectations mainly because the effects of cannabis are different for everyone. Also, do not replace RSO with a suggested form of treatment without consulting a doctor. Currently, no conclusive studies show that RSO can treat different conditions, including cancer. Therefore, consider this a complementary or alternative treatment.


RSO is a highly potent product of the cannabis plant that provides various therapeutic benefits, such as pain relief. This has led to an increase in the consumption of RSO for pain management. If you’re a newbie, it’s best to start in small doses and increase as you get accustomed to it.

It’s also natural to experience side effects such as irritability and anxiety. You can curb these effects by taking them in moderation. If you’re interested in using RSO oil for pain relief or managing other health conditions, first consult with your primary physician. Once you get the go-ahead, you can include it in your treatment plan.

Do you want to learn more about RSO oil and other cannabis products and how they can help you manage your condition? Plan a visit to our  MMJ Health clinics in Florida, and our attendants will be happy to help.